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IL-1R1 signaling in TBI: assessing chronic impacts and neuroinflammatory dynamics in a mouse model of mild closed-head injury

Neuroinflammation contributes to secondary injury cascades following traumatic brain injury (TBI), with alternating waves of inflammation and resolution. Interleukin-1 (IL-1), a critical neuroinflammatory mediator originating from brain endothelial cells, microglia, astrocytes, and peripheral immune...

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Detalles Bibliográficos
Autores principales: Vincent, Jonathan C., Garnett, Colleen N., Watson, James B., Higgins, Emma K., Macheda, Teresa, Sanders, Lydia, Roberts, Kelly N., Shahidehpour, Ryan K., Blalock, Eric M., Quan, Ning, Bachstetter, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601112/
https://www.ncbi.nlm.nih.gov/pubmed/37884959
http://dx.doi.org/10.1186/s12974-023-02934-3