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Meteorin-like/Meteorin-β protects LPS-induced acute lung injury by activating SIRT1-P53-SLC7A11 mediated ferroptosis pathway

BACKGROUND: Ferroptosis plays an essential role in lipopolysaccharide (LPS)-induced acute lung injury (ALI). Meteorin-like/Meteorin-β (Metrnβ) is a protein secreted by skeletal muscle and adipose tissue and plays a role in cardiovascular diseases. However, its role in acute lung injury has not been...

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Detalles Bibliográficos
Autores principales: Chen, Zhen, Li, Jun, Peng, Huan, Zhang, Mengli, Wu, Xian, Gui, Feng, Li, Wei, Ai, Fen, Yu, Bo, Liu, Yijue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601160/
https://www.ncbi.nlm.nih.gov/pubmed/37880599
http://dx.doi.org/10.1186/s10020-023-00714-6