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Proarrhythmic changes in human cardiomyocytes during hypothermia by milrinone and isoprenaline, but not levosimendan: an experimental in vitro study

BACKGROUND: Accidental hypothermia, recognized by core temperature below 35 °C, is a lethal condition with a mortality rate up to 25%. Hypothermia-induced cardiac dysfunction causing increased total peripheral resistance and reduced cardiac output contributes to the high mortality rate in this patie...

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Detalles Bibliográficos
Autores principales: Selli, Anders Lund, Ghasemi, Mohammadreza, Watters, Taylor, Burton, Francis, Smith, Godfrey, Dietrichs, Erik Sveberg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601188/
https://www.ncbi.nlm.nih.gov/pubmed/37880801
http://dx.doi.org/10.1186/s13049-023-01134-5