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Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity
BACKGROUND: The astrocytes in the central nervous system (CNS) exhibit morphological and functional diversity in brain region-specific pattern. Functional alterations of reactive astrocytes are commonly present in human temporal lobe epilepsy (TLE) cases, meanwhile the neuroinflammation mediated by...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601220/ https://www.ncbi.nlm.nih.gov/pubmed/37880726 http://dx.doi.org/10.1186/s12974-023-02909-4 |