Cell-specific NFIA upregulation promotes epileptogenesis by TRPV4-mediated astrocyte reactivity

BACKGROUND: The astrocytes in the central nervous system (CNS) exhibit morphological and functional diversity in brain region-specific pattern. Functional alterations of reactive astrocytes are commonly present in human temporal lobe epilepsy (TLE) cases, meanwhile the neuroinflammation mediated by...

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Detalles Bibliográficos
Autores principales: Kong, Shuo, Chen, Tao-xiang, Jia, Xiang-lei, Cheng, Xue-lei, Zeng, Meng-liu, Liang, Jing-yi, He, Xiao-hua, Yin, Jun, Han, Song, Liu, Wan-hong, Fan, Yuan-teng, Zhou, Ting, Liu, Yu-min, Peng, Bi-wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601220/
https://www.ncbi.nlm.nih.gov/pubmed/37880726
http://dx.doi.org/10.1186/s12974-023-02909-4

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