TreeKernel: interpretable kernel machine tests for interactions between -omics and clinical predictors with applications to metabolomics and COPD phenotypes

BACKGROUND: In this paper, we are interested in interactions between a high-dimensional -omics dataset and clinical covariates. The goal is to evaluate the relationship between a phenotype of interest and a high-dimensional omics pathway, where the effect of the omics data depends on subjects’ clini...

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Detalles Bibliográficos
Autores principales: Carpenter, Charlie M., Gillenwater, Lucas, Bowler, Russell, Kechris, Katerina, Ghosh, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601228/
https://www.ncbi.nlm.nih.gov/pubmed/37880571
http://dx.doi.org/10.1186/s12859-023-05459-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601228/
https://www.ncbi.nlm.nih.gov/pubmed/37880571
http://dx.doi.org/10.1186/s12859-023-05459-x

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