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Systematic engineering pinpoints a versatile strategy for the expression of functional cytochrome P450 enzymes in Escherichia coli cell factories

Production of plant secondary metabolites in engineered microorganisms provides a scalable and sustainable alternative to their sourcing from nature or through chemical synthesis. However, the biosynthesis of many valuable plant-derived products relies on cytochromes P450 – enzymes notoriously diffi...

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Detalles Bibliográficos
Autores principales: Poborsky, Michal, Crocoll, Christoph, Motawie, Mohammed Saddik, Halkier, Barbara Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601251/
https://www.ncbi.nlm.nih.gov/pubmed/37880718
http://dx.doi.org/10.1186/s12934-023-02219-7