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The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway

BACKGROUND: Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylhydrolase-like 1 (ADPRHL1), a pseudoenzyme belonging to a small group of ADP-ribosylhydrolase enzymes that lacks the amino acid residues necessary for catalytic activi...

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Detalles Bibliográficos
Autores principales: Tian, Lei, Guo, Tianwei, Wu, Fujian, Bai, Rui, Ai, Sinan, Wang, Hongyue, Song, Yuanxiu, Zhu, Min, Jiang, Youxu, Ma, Shuhong, Zhuang, Xiaofeng, Guo, Shuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601310/
https://www.ncbi.nlm.nih.gov/pubmed/37880701
http://dx.doi.org/10.1186/s13287-023-03507-0