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The pseudoenzyme ADPRHL1 affects cardiac function by regulating the ROCK pathway
BACKGROUND: Pseudoenzymes, catalytically deficient variants of active enzymes, have a wide range of regulatory functions. ADP-ribosylhydrolase-like 1 (ADPRHL1), a pseudoenzyme belonging to a small group of ADP-ribosylhydrolase enzymes that lacks the amino acid residues necessary for catalytic activi...
Autores principales: | Tian, Lei, Guo, Tianwei, Wu, Fujian, Bai, Rui, Ai, Sinan, Wang, Hongyue, Song, Yuanxiu, Zhu, Min, Jiang, Youxu, Ma, Shuhong, Zhuang, Xiaofeng, Guo, Shuzhen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601310/ https://www.ncbi.nlm.nih.gov/pubmed/37880701 http://dx.doi.org/10.1186/s13287-023-03507-0 |
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