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Paeoniflorin alleviates hypoxia/reoxygenation injury in HK-2 cells by inhibiting apoptosis and repressing oxidative damage via Keap1/Nrf2/HO-1 pathway

Acute kidney injury (AKI) is a serious disorder associated with significant morbidity and mortality. AKI and ischemia/reperfusion (hypoxia/reoxygenation, H/R) injury can be induced due to several reasons. Paeoniflorin (PF) is a traditional herbal medicine derived from Paeonia lactiflora Pall. It exe...

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Detalles Bibliográficos
Autores principales: Xing, Di, Ma, Yihua, Lu, Miaomiao, Liu, Wenlin, Zhou, Hongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601317/
https://www.ncbi.nlm.nih.gov/pubmed/37884904
http://dx.doi.org/10.1186/s12882-023-03366-0