Regulation of self-renewal and senescence in primitive mesenchymal stem cells by Wnt and TGFβ signaling

BACKGROUND: The therapeutic application of multipotent mesenchymal stem cells (MSCs) encounters significant challenges, primarily stemming from their inadequate growth and limited self-renewal capabilities. Additionally, as MSCs are propagated, their ability to self-renew declines, and the exact cel...

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Detalles Bibliográficos
Autores principales: Mazzella, Matteo, Walker, Keegan, Cormier, Christina, Kapanowski, Michael, Ishmakej, Albi, Saifee, Azeem, Govind, Yashvardhan, Chaudhry, G. Rasul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601332/
https://www.ncbi.nlm.nih.gov/pubmed/37880755
http://dx.doi.org/10.1186/s13287-023-03533-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601332/
https://www.ncbi.nlm.nih.gov/pubmed/37880755
http://dx.doi.org/10.1186/s13287-023-03533-y

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