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Regulation of self-renewal and senescence in primitive mesenchymal stem cells by Wnt and TGFβ signaling
BACKGROUND: The therapeutic application of multipotent mesenchymal stem cells (MSCs) encounters significant challenges, primarily stemming from their inadequate growth and limited self-renewal capabilities. Additionally, as MSCs are propagated, their ability to self-renew declines, and the exact cel...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601332/ https://www.ncbi.nlm.nih.gov/pubmed/37880755 http://dx.doi.org/10.1186/s13287-023-03533-y |