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Anti-cancer effect of palmatine through inhibition of the PI3K/AKT pathway in canine mammary gland tumor CMT-U27 cells

Canine mammary gland tumors (CMTs) are the most common and lethal cancers in female dogs. Dysregulated phosphoinositide 3-kinases (PI3K)/AKT pathway reportedly was involved in the growth and metastasis of CMTs. However, there are few studies on therapeutic strategies for targeting the PI3K pathway i...

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Detalles Bibliográficos
Autores principales: Yoo, Min-Jae, Choi, Jawun, Jang, Ye-ji, Park, Sang-Youel, Seol, Jae-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601335/
https://www.ncbi.nlm.nih.gov/pubmed/37880653
http://dx.doi.org/10.1186/s12917-023-03782-2