Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates

BACKGROUND: RNA velocity analysis of single cells offers the potential to predict temporal dynamics from gene expression. In many systems, RNA velocity has been observed to produce a vector field that qualitatively reflects known features of the system. However, the limitations of RNA velocity estim...

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Detalles Bibliográficos
Autores principales: Zheng, Shijie C., Stein-O’Brien, Genevieve, Boukas, Leandros, Goff, Loyal A., Hansen, Kasper D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601342/
https://www.ncbi.nlm.nih.gov/pubmed/37885016
http://dx.doi.org/10.1186/s13059-023-03065-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601342/
https://www.ncbi.nlm.nih.gov/pubmed/37885016
http://dx.doi.org/10.1186/s13059-023-03065-x

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