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Pumping the brakes on RNA velocity by understanding and interpreting RNA velocity estimates
BACKGROUND: RNA velocity analysis of single cells offers the potential to predict temporal dynamics from gene expression. In many systems, RNA velocity has been observed to produce a vector field that qualitatively reflects known features of the system. However, the limitations of RNA velocity estim...
Autores principales: | Zheng, Shijie C., Stein-O’Brien, Genevieve, Boukas, Leandros, Goff, Loyal A., Hansen, Kasper D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601342/ https://www.ncbi.nlm.nih.gov/pubmed/37885016 http://dx.doi.org/10.1186/s13059-023-03065-x |
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