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Exploration of DPP-IV Inhibitory Peptide Design Rules Assisted by the Deep Learning Pipeline That Identifies the Restriction Enzyme Cutting Site

[Image: see text] The mining of antidiabetic dipeptidyl peptidase IV (DPP-IV) inhibitory peptides (DPP-IV-IPs) is currently a costly and laborious process. Due to the absence of rational peptide design rules, it relies on cumbersome screening of unknown enzyme hydrolysates. Here, we present an enhan...

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Detalles Bibliográficos
Autores principales: Guan, Changge, Luo, Jiawei, Li, Shucheng, Tan, Zheng Lin, Wang, Yi, Chen, Haihong, Yamamoto, Naoyuki, Zhang, Chong, Lu, Yuan, Chen, Junjie, Xing, Xin-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601436/
https://www.ncbi.nlm.nih.gov/pubmed/37901493
http://dx.doi.org/10.1021/acsomega.3c05571