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A window into the human immune system: comprehensive characterization of the complexity of antibody complementary-determining regions in functional antibodies

The human immune system uses antibodies to neutralize foreign antigens. They are composed of heavy and light chains, both with constant and variable regions. The variable region has six hypervariable loops, also known as complementary-determining regions (CDRs) that determine antibody diversity and...

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Detalles Bibliográficos
Autores principales: Mejias-Gomez, Oscar, Madsen, Andreas V., Skovgaard, Kerstin, Pedersen, Lasse E., Morth, J. Preben, Jenkins, Timothy P., Kristensen, Peter, Goletz, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601506/
https://www.ncbi.nlm.nih.gov/pubmed/37876265
http://dx.doi.org/10.1080/19420862.2023.2268255