Cargando…

AIM2 fosters lung adenocarcinoma immune escape by modulating PD-L1 expression in tumor-associated macrophages via JAK/STAT3

This work was devised to discuss the effect of AIM2 on the immunosuppression of LUAD tumors, as well as its molecular mechanism. An allograft mouse model was built. Mouse macrophages were isolated and collected. The infiltration level of Mø and expression of M1 Mø, M2 Mø markers, and PD-L1 were assa...

Descripción completa

Detalles Bibliográficos
Autores principales: Ye, Hua, Yu, Wenwen, Li, Yunlei, Bao, Xiaoqiong, Ni, Yangyang, Chen, Xiangxiang, Sun, Yangjie, Chen, Ali, Zhou, Weilong, Li, Jifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601527/
https://www.ncbi.nlm.nih.gov/pubmed/37877820
http://dx.doi.org/10.1080/21645515.2023.2269790