PIH1D3-knockout rats exhibit full ciliopathy features and dysfunctional pre-assembly and loading of dynein arms in motile cilia

Background: Recessive mutation of the X-linked gene, PIH1 domain-containing protein 3 (PIH1D3), causes familial ciliopathy. PIH1D3 deficiency is associated with the defects of dynein arms in cilia, but how PIH1D3 specifically affects the structure and function of dynein arms is not understood yet. T...

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Detalles Bibliográficos
Autores principales: Zhang, Tingting, Cui, Shiquan, Xiong, Xinrui, Liu, Ying, Cao, Qilin, Xia, Xu-Gang, Zhou, Hongxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601634/
https://www.ncbi.nlm.nih.gov/pubmed/37900281
http://dx.doi.org/10.3389/fcell.2023.1282787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10601634/
https://www.ncbi.nlm.nih.gov/pubmed/37900281
http://dx.doi.org/10.3389/fcell.2023.1282787

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