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Characterization of Novel Human β-glucocerebrosidase Antibodies for Parkinson Disease Research
BACKGROUND: Mutations in GBA1, which encodes the lysosome enzyme β-glucocerebrosidase (also referred to as acid β-glucosidase or GCase), are the most common genetic risk factor for Parkinson disease (PD) and dementia with Lewy bodies (DLB). Evidence also suggests that loss of GCase activity is impli...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602026/ https://www.ncbi.nlm.nih.gov/pubmed/37886493 http://dx.doi.org/10.1101/2023.09.14.557851 |