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Characterization of Novel Human β-glucocerebrosidase Antibodies for Parkinson Disease Research

BACKGROUND: Mutations in GBA1, which encodes the lysosome enzyme β-glucocerebrosidase (also referred to as acid β-glucosidase or GCase), are the most common genetic risk factor for Parkinson disease (PD) and dementia with Lewy bodies (DLB). Evidence also suggests that loss of GCase activity is impli...

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Detalles Bibliográficos
Autores principales:	Jong, Tiffany, Gehrlein, Alexandra, Sidransky, Ellen, Jagasia, Ravi, Chen, Yu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602026/ https://www.ncbi.nlm.nih.gov/pubmed/37886493 http://dx.doi.org/10.1101/2023.09.14.557851

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