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A beneficial synonymous substitution in EF-Tu is contingent on genetic background

Synonymous mutations are changes to DNA sequence that occur within translated genes but which do not affect the protein sequence. Although often referred to as silent mutations, evidence suggests that synonymous mutations can affect gene expression, mRNA stability, and even translation efficiency. A...

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Detalles Bibliográficos
Autores principales: McGrath, Kaitlyn M., Russell, Steven J., Fer, Evrim, Garmendia, Eva, Hosgel, Ali, Baltrus, David A., Kaçar, Betül
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602032/
https://www.ncbi.nlm.nih.gov/pubmed/37886545
http://dx.doi.org/10.1101/2023.09.06.555949