IgG sialylation occurs via the FcRn-mediated recycling pathway in endothelial cells

IgG is a key mediator of immune responses throughout the human body, and the structure of the conserved glycan on the Fc region has been identified as a key inflammatory switch regulating its downstream effects. In particular, the absence of terminal sialic acid has been shown to increase the affini...

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Detalles Bibliográficos
Autores principales: Glendenning, Leandre M., Reynero, Kalob M., Kukan, Emily N., Long, Megan D., Cobb, Brian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602034/
https://www.ncbi.nlm.nih.gov/pubmed/37886533
http://dx.doi.org/10.1101/2023.06.30.547255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602034/
https://www.ncbi.nlm.nih.gov/pubmed/37886533
http://dx.doi.org/10.1101/2023.06.30.547255

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