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IgG sialylation occurs via the FcRn-mediated recycling pathway in endothelial cells
IgG is a key mediator of immune responses throughout the human body, and the structure of the conserved glycan on the Fc region has been identified as a key inflammatory switch regulating its downstream effects. In particular, the absence of terminal sialic acid has been shown to increase the affini...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602034/ https://www.ncbi.nlm.nih.gov/pubmed/37886533 http://dx.doi.org/10.1101/2023.06.30.547255 |