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Genetics of NLRP3 suggests lack of involvement and inefficient druggability in Parkinson’s disease
Activation of the NLRP3-inflammasome has been proposed to play a role in Parkinson’s disease pathogenesis based on in vitro and in vivo studies. Currently, clinical trials targeting the NLRP3 pathway in Parkinson’s disease are at early stages. However, the evidence supporting NLRP3’s involvement in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602039/ https://www.ncbi.nlm.nih.gov/pubmed/37886468 http://dx.doi.org/10.1101/2023.09.20.23295790 |