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Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states

Schlemm’s canal (SC) is central in intraocular pressure regulation but requires much characterization. It has distinct inner and outer walls, each composed of Schlemm’s canal endothelial cells (SECs) with different morphologies and functions. Recent transcriptomic studies of the anterior segment add...

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Detalles Bibliográficos
Autores principales: Balasubramanian, Revathi, Kizhatil, Krishnakumar, Li, Taibo, Tolman, Nicholas, Bhandari, Aakriti, Clark, Graham, Bupp-Chickering, Violet, Zhou, Sally, Peregrin, John, Simón, Marina, Montgomery, Christa, Qian, Jiang, John, Simon W.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602040/
https://www.ncbi.nlm.nih.gov/pubmed/37886472
http://dx.doi.org/10.1101/2023.08.31.555823