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Cortical lesions uniquely predict motor disability accrual and form rarely in the absence of new white matter lesions in multiple sclerosis

BACKGROUND AND OBJECTIVES: Cortical lesions (CL) are common in multiple sclerosis (MS) and associate with disability and progressive disease. We asked whether CL continue to form in people with stable white matter lesions (WML) and whether the association of CL with worsening disability relates to p...

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Detalles Bibliográficos
Autores principales: Beck, Erin S, Mullins, W Andrew, dos Santos Silva, Jonadab, Filippini, Stefano, Parvathaneni, Prasanna, Maranzano, Josefina, Morrison, Mark, Suto, Daniel J, Donnay, Corinne, Dieckhaus, Henry, Luciano, Nicholas J, Sharma, Kanika, Gaitán, María Ines, Liu, Jiaen, de Zwart, Jacco A, van Gelderen, Peter, Cortese, Irene, Narayanan, Sridar, Duyn, Jeff H, Nair, Govind, Sati, Pascal, Reich, Daniel S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602044/
https://www.ncbi.nlm.nih.gov/pubmed/37886541
http://dx.doi.org/10.1101/2023.09.22.23295974