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The endogenous opioid system in the medial prefrontal cortex mediates ketamine’s antidepressant-like actions

Recent studies have implicated the endogenous opioid system in the antidepressant actions of ketamine, but the underlying mechanisms remain unclear. We used a combination of pharmacological, behavioral, and molecular approaches in rats to test the contribution of the prefrontal endogenous opioid sys...

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Detalles Bibliográficos
Autores principales: Pittenger, Christopher, Jiang, Cheng, DiLeone, Ralph, Duman, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602058/
https://www.ncbi.nlm.nih.gov/pubmed/37886526
http://dx.doi.org/10.21203/rs.3.rs-3190391/v1