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Chemokine-derived oncolytic peptide induces immunogenic cancer cell death and significantly suppresses tumor growth

Chemokinostatin-1 (CKS1) is a 24-mer peptide originally discovered as an anti-angiogenic peptide derived from the CXCL1 chemokine. Here, we demonstrate that CKS1 acts not only as an anti-angiogenic peptide but also as an oncolytic peptide due to its structural and physical properties. CKS1 induced b...

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Detalles Bibliográficos
Autores principales: Furukawa, Natsuki, Yang, Wendy, Chao, Alex, Patil, Akash, Mirando, Adam, Pandey, Niranjan, Popel, Aleksander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602061/
https://www.ncbi.nlm.nih.gov/pubmed/37886580
http://dx.doi.org/10.21203/rs.3.rs-3335225/v1