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Bayesian-frequentist hybrid inference framework for single cell RNA-seq analyses

BACKGROUND: Single cell RNA sequencing technology (scRNA-seq) has been proven useful in understanding cell-specific disease mechanisms. However, identifying genes of interest remains a key challenge. Pseudo-bulk methods that pool scRNA-seq counts in the same biological replicates have been commonly...

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Detalles Bibliográficos
Autores principales: Han, Gang, Yan, Dongyan, Sun, Zhe, Fang, Jiyuan, chang, Xinyue, Wilson, Lucas, Liu, Yushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602069/
https://www.ncbi.nlm.nih.gov/pubmed/37886581
http://dx.doi.org/10.21203/rs.3.rs-3384541/v1