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Anionic Nanoplastic Contaminants Promote Parkinson’s Disease-Associated α-Synuclein Aggregation

Recent studies have identified increasing levels of nanoplastic pollution in the environment. Here we find that anionic nanoplastic contaminants potently precipitate the formation and propagation of α-synuclein protein fibrils through a high-affinity interaction with the amphipathic and non-amyloid...

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Detalles Bibliográficos
Autores principales: Liu, Zhiyong, Sokratian, Arpine, Duda, Addison M., Xu, Enquan, Stanhope, Christina, Fu, Amber, Strader, Samuel, Li, Huizhong, Yuan, Yuan, Bobay, Benjamin G., Sipe, Joana, Bai, Ketty, Lundgaard, Iben, Liu, Na, Hernandez, Belinda, Rickman, Catherine Bowes, Miller, Sara E, West, Andrew B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602106/
https://www.ncbi.nlm.nih.gov/pubmed/37886561
http://dx.doi.org/10.21203/rs.3.rs-3439102/v1