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Anionic Nanoplastic Contaminants Promote Parkinson’s Disease-Associated α-Synuclein Aggregation
Recent studies have identified increasing levels of nanoplastic pollution in the environment. Here we find that anionic nanoplastic contaminants potently precipitate the formation and propagation of α-synuclein protein fibrils through a high-affinity interaction with the amphipathic and non-amyloid...
Autores principales: | Liu, Zhiyong, Sokratian, Arpine, Duda, Addison M., Xu, Enquan, Stanhope, Christina, Fu, Amber, Strader, Samuel, Li, Huizhong, Yuan, Yuan, Bobay, Benjamin G., Sipe, Joana, Bai, Ketty, Lundgaard, Iben, Liu, Na, Hernandez, Belinda, Rickman, Catherine Bowes, Miller, Sara E, West, Andrew B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602106/ https://www.ncbi.nlm.nih.gov/pubmed/37886561 http://dx.doi.org/10.21203/rs.3.rs-3439102/v1 |
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