Translating GWAS Findings to Inform Drug Repositioning Strategies for COVID-19 Treatment

We developed a computational framework that integrates Genome-Wide Association Studies (GWAS) and post-GWAS analyses, designed to facilitate drug repurposing for COVID-19 treatment. The comprehensive approach combines transcriptomic-wide associations, polygenic priority scoring, 3D genomics, viral-h...

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Detalles Bibliográficos
Autores principales: Tsai, Ming-Ju, Jeong, Sohyun, Yu, Fangtang, Chen, Ting-Fu, Li, Peng-Hsuan, Juan, Hsueh-Fen, Huang, Jia-Hsin, Hsu, Yi-Hsiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602133/
https://www.ncbi.nlm.nih.gov/pubmed/37886583
http://dx.doi.org/10.21203/rs.3.rs-3443080/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602133/
https://www.ncbi.nlm.nih.gov/pubmed/37886583
http://dx.doi.org/10.21203/rs.3.rs-3443080/v1

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