Self-reactive germline-like TCR alpha chains shared between blood and pancreas

Human islet antigen reactive CD4 + memory T cells (IAR T cells) from peripheral blood have been studied extensively for their role in the pathogenesis of autoimmune type 1 diabetes (T1D). However, IAR T cells are rare, and it remains poorly understood how they affect T1D progression in the pancreas....

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Detalles Bibliográficos
Autores principales: Linsley, Peter, Nakayama, Maki, Balmas, Elisa, Chen, Janice, Pour, Fariba, Bansal, Shubham, Serti, Elisavet, Speake, Cate, Pugliese, Alberto, Cerosaletti, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602137/
https://www.ncbi.nlm.nih.gov/pubmed/37886513
http://dx.doi.org/10.21203/rs.3.rs-3446917/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602137/
https://www.ncbi.nlm.nih.gov/pubmed/37886513
http://dx.doi.org/10.21203/rs.3.rs-3446917/v1

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