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Self-reactive germline-like TCR alpha chains shared between blood and pancreas
Human islet antigen reactive CD4 + memory T cells (IAR T cells) from peripheral blood have been studied extensively for their role in the pathogenesis of autoimmune type 1 diabetes (T1D). However, IAR T cells are rare, and it remains poorly understood how they affect T1D progression in the pancreas....
Autores principales: | Linsley, Peter, Nakayama, Maki, Balmas, Elisa, Chen, Janice, Pour, Fariba, Bansal, Shubham, Serti, Elisavet, Speake, Cate, Pugliese, Alberto, Cerosaletti, Karen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602137/ https://www.ncbi.nlm.nih.gov/pubmed/37886513 http://dx.doi.org/10.21203/rs.3.rs-3446917/v1 |
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