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Selective RNAi-silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury

We previously reported functional Piezo1 expression in Schwann cells of the peripheral nervous system. This study is designed to further investigate the role of Schwann cell Piezo1 in peripheral nociception. We first developed an adeno-associated viral (AAV) vector that has primary Schwann cell trop...

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Detalles Bibliográficos
Autores principales: Itson-Zoske, Brandon, Gani, Uarda, Mikesell, Alexander, Qiu, Chengsheng, Fan, Fan, Stucky, Cheryl, Hogan, Quinn, Shin, Seung Min, Yu, Hongwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602140/
https://www.ncbi.nlm.nih.gov/pubmed/37886453
http://dx.doi.org/10.21203/rs.3.rs-3405016/v1