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Selective RNAi-silencing of Schwann cell Piezo1 alleviates mechanical hypersensitization following peripheral nerve injury
We previously reported functional Piezo1 expression in Schwann cells of the peripheral nervous system. This study is designed to further investigate the role of Schwann cell Piezo1 in peripheral nociception. We first developed an adeno-associated viral (AAV) vector that has primary Schwann cell trop...
Autores principales: | Itson-Zoske, Brandon, Gani, Uarda, Mikesell, Alexander, Qiu, Chengsheng, Fan, Fan, Stucky, Cheryl, Hogan, Quinn, Shin, Seung Min, Yu, Hongwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602140/ https://www.ncbi.nlm.nih.gov/pubmed/37886453 http://dx.doi.org/10.21203/rs.3.rs-3405016/v1 |
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