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Therapeutic Intervention of Neuroinflammatory Alzheimer Disease Model by Inhibition of Classical Complement Pathway with the Use of Anti-C1r Loaded Exosomes

Alzheimer’s disease (AD) is a complex neurodegenerative disease associated with memory decline, cognitive impairment, amyloid plaque formation and tau tangles. Neuroinflammation has been shown to be a precursor to apparent amyloid plaque accumulation and subsequent synaptic loss and cognitive declin...

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Detalles Bibliográficos
Autores principales: Richards, Terjahna, Perron, Jeanette C., Patel, Ketan, Wurpel, John, Reznik, Sandra E., Schanne, Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602145/
https://www.ncbi.nlm.nih.gov/pubmed/37886595
http://dx.doi.org/10.21203/rs.3.rs-3399248/v1