Cargando…
Therapeutic Intervention of Neuroinflammatory Alzheimer Disease Model by Inhibition of Classical Complement Pathway with the Use of Anti-C1r Loaded Exosomes
Alzheimer’s disease (AD) is a complex neurodegenerative disease associated with memory decline, cognitive impairment, amyloid plaque formation and tau tangles. Neuroinflammation has been shown to be a precursor to apparent amyloid plaque accumulation and subsequent synaptic loss and cognitive declin...
Autores principales: | Richards, Terjahna, Perron, Jeanette C., Patel, Ketan, Wurpel, John, Reznik, Sandra E., Schanne, Francis |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Journal Experts
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602145/ https://www.ncbi.nlm.nih.gov/pubmed/37886595 http://dx.doi.org/10.21203/rs.3.rs-3399248/v1 |
Ejemplares similares
-
Endogenous Lipid Carriers—Bench-to-Bedside Roadblocks in Production and Drug Loading of Exosomes
por: Richards, Terjahna, et al.
Publicado: (2023) -
Crry silencing alleviates Alzheimer’s disease injury by regulating neuroinflammatory cytokines and the complement system
por: Zhu, Xi-Chen, et al.
Publicado: (2022) -
Microglia in the Neuroinflammatory Pathogenesis of Alzheimer’s Disease and Related Therapeutic Targets
por: Cai, Yongle, et al.
Publicado: (2022) -
Plasma Exosomes Contribute to Microvascular Damage in Diabetic Retinopathy by Activating the Classical Complement Pathway
por: Huang, Chao, et al.
Publicado: (2018) -
Free complement and complement containing extracellular vesicles as potential biomarkers for neuroinflammatory and neurodegenerative disorders
por: Burgelman, Marlies, et al.
Publicado: (2023)