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Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study

Lithium is the gold standard treatment for bipolar disorder (BD). However, its mechanism of action is incompletely understood, and prediction of treatment outcomes is limited. In our previous multi-omics study of the Pharmacogenomics of Bipolar Disorder (PGBD) sample combining transcriptomic and gen...

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Autores principales: Kelsoe, John, Ou, Anna, Rosenthal, Sara, Adli, Mazda, Akiyama, Kazufumi, Akula, Nirmala, Alda, Martin, Amare, Azmeraw T., Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Banzato, Claudio, Bauer, Michael, Baune, Bernhard, Bellivier, Frank, Benabarre, Antonio, Bengesser, Susanne, Abesh, Bhattacharjee, Biernacka, Joanna, Bui, Elise, Cervantes, Pablo, Chen, Guo-Bo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven, Clark, Scott, Colom, Francesc, Cousins, David, Cruceanu, Cristiana, Czerski, Piotr, Dantas, Clarissa, Dayer, Alexandre, Degenhardt, Franziska, DePaulo, J. Raymond, Etain, Bruno, Falkai, Peter, Fellendorf, Frederike, Ferensztajn-Rochowiak, Ewa, Forstner, Andreas J., Frisen, Louise, Frye, Mark, Fullerton, Janice, Gard, Sebastien, Garnham, Julie, Goes, Fernando, Grigoroiu-Serbanescu, Maria, Grof, Paul, Gruber, Oliver, Hashimoto, Ryota, Hauser, Joanna, Heilbronner, Urs, Herms, Stefan, Hoffmann, Per, Hofmann, Andrea, Hou, Liping, Jamain, Stéphane, Jiménez, Esther, Kahn, Jean-Pierre, Kassem, Layla, Kato, Tadafumi, Kittel-Schneider, Sarah, König, Barbara, kuo, Po-Hsiu, Kusumi, Ichiro, Dalkner, Nina, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan, Jaramillo, Carlos López, MacQueen, Glenda, Maj, Mario, Manchia, Mirko, Marie-Claire, Cynthia, Martinsson, Lina, Mattheisen, Manuel, McCarthy, Michael, McElroy, Susan, McMahon, Francis, Mitchell, Philip, Mitjans, Marina, Mondimore, Francis, Monteleone, Palmiero, Nievergelt, Caroline, Nöthen, Markus, Novak, Tomas, Osby, Urban, Ozaki, Norio, Papiol, Sergi, Perlis, Roy, Pfennig, Andrea, Potash, James, Reich-Erkelenz, Daniela, Reif, Andreas, Reininghaus, Eva, Rietschel, Marcella, Rouleau, Guy, Rybakowski, Janusz K., Schalling, Martin, Schofield, Peter, Schubert, Klaus Oliver, Schulze, Thomas, SCHWEIZER, BARBARA, Seemüller, Florian, Severino, Giovanni, Shekhtman, Tatyana, Shilling, Paul, Shimoda, Kazutaka, Simhandl, Christian, slaney, claire, Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Tighe, Sarah, Tortorella, Alfonso, Turecki, Gustavo, Vieta, Eduard, Volkert, Julia, Witt, Stephanie, Wray, Naomi, Wright, Adam, Young, Trevor, Zandi, Peter, Zompo, Maria Del
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602152/
https://www.ncbi.nlm.nih.gov/pubmed/37886563
http://dx.doi.org/10.21203/rs.3.rs-3258813/v1