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Genetic or pharmacological GHSR blockade has sexually dimorphic effects in rodents on a high-fat diet

The stomach-derived hormone ghrelin regulates essential physiological functions. The ghrelin receptor (GHSR) has ligand-independent actions, therefore, GHSR gene deletion may be a reasonable approach to investigate the role of this system in feeding behaviors and diet-induced obesity (DIO). Here we...

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Detalles Bibliográficos
Autores principales: Leggio, Lorenzo, Leko, Andras, Gregory-Flores, Adriana, Marchette, Renata, Gomez, Juan, Vendruscolo, Janaina, Repunte-Canonigo, Vez, Chuong, Vicky, Deschaine, Sara, Whiting, Kimberly, Jackson, Shelley, Cornejo, Maria, Perello, Mario, You, Zhi-Bing, Eckhaus, Michael, Janda, Kim, Zorman, Barry, Sumazin, Pavel, Koob, George, Michaelides, Michael, Sanna, Pietro Paolo, Vendruscolo, Leandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602167/
https://www.ncbi.nlm.nih.gov/pubmed/37886546
http://dx.doi.org/10.21203/rs.3.rs-3236045/v1