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HIV-1 mRNA Knockdown with CRISPR/Cas9 Enhances Neurocognitive Function

Mixed glia are infiltrated with HIV-1 virus early in the course of infection leading to the development of a persistent viral reservoir in the central nervous system. Modification of the HIV-1 genome using gene editing techniques, including CRISPR/Cas9, has shown great promise towards eliminating HI...

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Detalles Bibliográficos
Autores principales: McLaurin, Kristen A, Li, Hailong, Khalili, Kamel, Mactutus, Charles F., Booze, Rosemarie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602171/
https://www.ncbi.nlm.nih.gov/pubmed/37886577
http://dx.doi.org/10.21203/rs.3.rs-3266933/v1