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Simultaneous Inhibition of PI3K and PAK in Preclinical Models of Neurofibromatosis Type 2-related Schwannomatosis

Neurofibromatosis Type 2 (NF2)-related schwannomatosis is a genetic disorder that causes development of multiple types of nervous system tumors. The primary and diagnostic tumor type is bilateral vestibular schwannoma. There is no cure or drug therapy for NF2. Recommended treatments include surgical...

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Detalles Bibliográficos
Autores principales: Fernandez-Valle, Cristina, Nagel, Anna, Huegel, Julianne, Petrilli, Alejandra, Rosario, Rosa, Victoria, Berta, Hardin, Haley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602174/
https://www.ncbi.nlm.nih.gov/pubmed/37886501
http://dx.doi.org/10.21203/rs.3.rs-3405297/v1