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RNA-seq RNAaccess identified as the preferred method for gene expression analysis of low quality FFPE samples

Clinical tumor tissues that are preserved as formalin-fixed paraffin-embedded (FFPE) samples result in extensive cross-linking, fragmentation, and chemical modification of RNA, posing significant challenges for RNA-seq-based gene expression profiling. This study sought to define an optimal RNA-seq p...

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Detalles Bibliográficos
Autores principales: Song, Kai, Elboudwarej, Emon, Zhao, Xi, Zhuo, Luting, Pan, David, Liu, Jinfeng, Brachmann, Carrie, Patterson, Scott D., Yoon, Oh Kyu, Zavodovskaya, Marianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602291/
https://www.ncbi.nlm.nih.gov/pubmed/37883360
http://dx.doi.org/10.1371/journal.pone.0293400