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Immunotherapy-induced cytotoxic T follicular helper cells reduce numbers of retrovirus-infected reservoir cells in B cell follicles

Antiretroviral therapy (ART) transformed HIV from a life-threatening disease to a chronic condition. However, eliminating the virus remains an elusive therapy goal. For several decades, Friend virus (FV) infection serves as a murine model to study retrovirus immunity. Similar to HIV, FV persists at...

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Detalles Bibliográficos
Autores principales: Malyshkina, Anna, Bayer, Wibke, Podschwadt, Philip, Otto, Lucas, Karakoese, Zehra, Sutter, Kathrin, Bruderek, Kirsten, Wang, Baoxiao, Lavender, Kerry J., Santiago, Mario L., Leipe, Pia Madeleine, Elsner, Carina, Esser, Stefan, Brandau, Sven, Gunzer, Matthias, Dittmer, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602292/
https://www.ncbi.nlm.nih.gov/pubmed/37883584
http://dx.doi.org/10.1371/journal.ppat.1011725