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Virally encoded interleukin-6 facilitates KSHV replication in monocytes and induction of dysfunctional macrophages

Kaposi’s sarcoma-associated herpesvirus (KSHV) is an oncogenic double-stranded DNA virus and the etiologic agent of Kaposi’s sarcoma and hyperinflammatory lymphoproliferative disorders. Understanding the mechanism by which KSHV increases the infected cell population is crucial for curing KSHV-associ...

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Detalles Bibliográficos
Autores principales: Shimoda, Michiko, Inagaki, Tomoki, Davis, Ryan R., Merleev, Alexander, Tepper, Clifford G., Maverakis, Emanual, Izumiya, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602306/
https://www.ncbi.nlm.nih.gov/pubmed/37883374
http://dx.doi.org/10.1371/journal.ppat.1011703