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A randomized controlled trial of teprenone in terms of preventing worsening of COVID-19 infection

BACKGROUND: Some COVID-19 patients develop life-threatening disease accompanied by severe pneumonitis. Teprenone induces expression of heat-shock proteins (HSPs) that protect against interstitial pneumonia in preclinical models. We explored whether teprenone prevented worsening of COVID-19 infection...

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Detalles Bibliográficos
Autores principales: Ichihara, Eiki, Hasegawa, Kou, Kudo, Kenichiro, Tanimoto, Yasushi, Nouso, Kazuhiro, Oda, Naohiro, Mitsumune, Sho, Yamada, Haruto, Takata, Ichiro, Hagiya, Hideharu, Mitsuhashi, Toshiharu, Taniguchi, Akihiko, Toyooka, Shinichi, Tsukahara, Kohei, Aokage, Toshiyuki, Tsukahara, Hirokazu, Kiura, Katsuyuki, Maeda, Yoshinobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602324/
https://www.ncbi.nlm.nih.gov/pubmed/37883347
http://dx.doi.org/10.1371/journal.pone.0287501