Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles

Microtubule-targeted agents are commonly used for cancer treatment, though many patients do not benefit. Microtubule-targeted drugs were assumed to elicit anticancer activity via mitotic arrest because they cause cell death following mitotic arrest in cell culture. However, we recently demonstrated...

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Detalles Bibliográficos
Autores principales: Zhou, Amber S., Tucker, John B., Scribano, Christina M., Lynch, Andrew R., Carlsen, Caleb L., Pop-Vicas, Sophia T., Pattaswamy, Srishrika M., Burkard, Mark E., Weaver, Beth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602348/
https://www.ncbi.nlm.nih.gov/pubmed/37883329
http://dx.doi.org/10.1371/journal.pbio.3002339

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602348/
https://www.ncbi.nlm.nih.gov/pubmed/37883329
http://dx.doi.org/10.1371/journal.pbio.3002339

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