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Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles
Microtubule-targeted agents are commonly used for cancer treatment, though many patients do not benefit. Microtubule-targeted drugs were assumed to elicit anticancer activity via mitotic arrest because they cause cell death following mitotic arrest in cell culture. However, we recently demonstrated...
Autores principales: | Zhou, Amber S., Tucker, John B., Scribano, Christina M., Lynch, Andrew R., Carlsen, Caleb L., Pop-Vicas, Sophia T., Pattaswamy, Srishrika M., Burkard, Mark E., Weaver, Beth A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602348/ https://www.ncbi.nlm.nih.gov/pubmed/37883329 http://dx.doi.org/10.1371/journal.pbio.3002339 |
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