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Metformin pretreatment ameliorates busulfan-induced liver endothelial toxicity during haematopoietic stem cell transplantation

The success of Haematopoietic cell transplantation (HCT) is often limited by regimen-related toxicity (RRT) caused by conditioning regimen drugs. Among different conditioning drugs, busulfan (Bu) and treosulfan (Treo), although widely used in HCT, exhibit different toxicity profiles, the mechanism o...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Balaji, Illangeswaran, Raveen Stephen Stallon, Rajamani, Bharathi Murugan, Arunachalam, Arun Kumar, Pai, Aswin Anand, Mohanan, Ezhilpavai, Srivastava, Alok, Mathews, Vikram, Balasubramanian, Poonkuzhali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10602364/
https://www.ncbi.nlm.nih.gov/pubmed/37883349
http://dx.doi.org/10.1371/journal.pone.0293311